Pentobarbital will reduce the level or influence of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust CYP3A4 inducers may result in decreased serum concentrations and lack of antimalarial efficacy pentobarbital will decrease the extent or effect of verapamil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.... https://ernestd321qco5.ltfblog.com/profile