Anaphylaxis: Anaphylaxis has become described with codeine, one of the ingredients in promethazine HCl and codeine phosphate oral Option. The opioid antagonists, naloxone and nalmefene, are distinct antidotes for respiratory despair ensuing from opioid overdose. For clinically major respiratory or circulatory depression secondary to codeine overdose, administer an opioid antagonist. https://alexishmmli.blogacep.com/37481844/5-simple-statements-about-akorn-codeine-explained