Due to this fact, more of a drug stays in your human body for an extended time. This raises your possibility of side effects. Seniors ages 65 a long time and older are at greater danger of side effects with the extended-release types of this drug. Sphincter of Oddi Spasm. https://raymondwoeth.thekatyblog.com/37040853/tramadol-vs-other-pain-medications-an-overview